The pipeline includes: (1) target selection; (2) cloning the coding sequence of the targets into an appropriate expression vector; (3) sequencing the cloned ...

Sep 2, 2007 · We present a brief summary of the process we used at the Berkeley Structural Genomics Center to infer molecular functions of proteins of unknown ...

Structural genomics (SG) is a relatively new branch of structural biology that refers to the exploration of protein structures on a genome scale.

Table 1: Inferred Enzymatic functions of BSGC structures with unknown function. Four BSGC structures indexed by their GI numbers and PDB IDs are listed in ...

A major challenge now involves the development of computational methods to assign functions to these proteins accurately and automatically. As part of the ...

Structural genomics aspires “to determine the three-dimensional shapes of all proteins and other important biomolecules encoded by the genomes of key organisms” ...

Structural genomics is a broad initiative of various centers aiming to provide complete coverage of protein structure space. Because it is not feasible to ...

We present a brief summary of the process we used at the Berkeley Structural Genomics Center to infer molecular functions of proteins of unknown function.

Many of the gene products of completely sequenced organisms are 'hypothetical' — they cannot be related to any previously characterized proteins — and so ...

Structural genomics centers worldwide have been determining many 3-D structures of the proteins of unknown functions, and possible molecular functions of them ...